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Decreased quinolinic acid in the hippocampus of depressive patients: evidence for local anti-inflammatory and neuroprotective responses

Intracellular anti-inflammatory effects via NF-kB inhibition outlast the plasma window

doi: 10.3390/nu15153363 10 Arteaga-MullerG

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Even though Coomassie Blue staining showed heterogeneity in protein size, incubation with peptide-N4-( N -acetyl-beta-glucosaminyl) asparagine amidase (PNGaseF) , a peptide-endoglycanase that removes high mannose, complex and hybrid N -glycans from proteins, homogenized all isoforms to a sharper band of 2526 kDa, compatible with the predicted molecular weights (MW) of deglycosylated RBD (26.5 kDa, Fig